新型环境污染物抗生素的分子生态毒理研究进展

生态学杂志 ›› 2010, Vol. 29 ›› Issue (10): 2042-2048.

新型环境污染物抗生素的分子生态毒理研究进展

董璐玺¹,谢秀杰¹,周启星^1,2**,黄盼盼¹

¹南开大学环境科学与工程学院,环境污染过程与基准教育部重点实验室,天津 300071;²中国科学院沈阳应用生态研究所,中国科学院陆地生态过程重点实验室,沈阳 11001

出版日期:2010-10-08 发布日期:2010-10-08

Molecular ecotoxicology of antibiotics, an emerging type of environmental contaminants: A review.

DONG Lu-xi¹, XIE Xiu-jie¹, ZHOU Qi-xing^1,2, HUANG Pan-pan¹

¹Key Laboratory of Pollution Processes and Environmental Criteria (Ministry of Education), College of Environmental Science and Engineering, Nankai University, Tianjin 300071, China|²Key Laboratory of Terrestrial Ecological Process, Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang 110016, China

Online:2010-10-08 Published:2010-10-08

摘要/Abstract

摘要： 人们在农业畜牧业和治疗人类疾病的过程中大量使用抗生素，由于抗生素自身独特的代谢特点，导致了抗生素在包括水体和土壤等环境介质中的残留，并因此导致对不同生物及生态系统产生广泛而深远的影响。本文概述了目前抗生素分子生态毒理学方面的研究进展，并阐述了抗生素对生物及生态系统的各分子水平的毒性机理及分子标记物研究情况，对于一些较新的分子诊断方法也进行了总结。最后，分析了抗生素分子生态毒理研究存在的不足，并探讨了今后的研究重点。

关键词: 甲基对硫磷, 发酵液, 上清, 菌体蛋白, 粗酶液, 洗涤剂

Abstract: In recent decades, antibiotics have been widely used as the medicines for human and livestock. However, a large percentage of ingested antibiotics in living organisms are not metabolized but excreted and released as toxic contaminants, inducing their incremental residue in soil and aquatic environment, and resulting in adverse effects on living organisms and ecosystems. This paper summarized the research progress in molecular ecotoxicology of antibiotics, molecular mechanisms of antibiotics toxicity to living organisms and ecosystems, and ecotoxicological studies on molecular biomarkers of antibiotics, and summed up the new molecular diagnostic techniques applied in ecotoxicology. Some deficiencies of current molecular ecotoxicological diagnosis were pointed out, and the future study on the ecotoxicology of antibiotics was prospected.

Key words: Methyl parathion, Ferment, Supernatant, Pellet extract, Crude enzyme, Detergent

董璐玺,谢秀杰,周启星,黄盼盼. 新型环境污染物抗生素的分子生态毒理研究进展[J]. 生态学杂志, 2010, 29(10): 2042-2048.