Based on previous studies, an ecological zoning index system of different maturity wine grapes in northern China were set up. Using the stepbystep stratification method and set optimization method, the authors studied ecological regionalization of different maturity wine grapes in northern China and made the regionalization map by support of GIS technology. The results showed that, in northern China, ecological area of early, mid and latematurity wine grapes can be divided into 5 categories: the most suitable, suitable, poorly suitable, not suitable and not planting. The most suitable ecological region of different maturity wine grapes were scattered in small areas, and not overlapped. The suitable areas are more widely distributed; although they were slightly overlapped, most of the areas were different. It is almost impossible that a given area is the most suitable ecological region for both early maturing varieties and late maturing varieties or mid maturing varieties. In wine grape industrial layout and raw material base establishment, the special needs of different maturity grapes for ecological factors should be considered, to ensure that the different maturity varieties are grown in the most suitable ecological zone.