Abstract: In any ecological restoration project in coastal areas, it is crucial to select suitable plant species with high salt tolerance and economic significance. In this study, Tetragonia tetragonoides seedlings were sand-cultured with nutritional solution of different salinities (0, 100, 200, 300, 400, and 600 mmol·L^-1), and the seedling growth indices, biomass, and photosynthetic and chlorophyll fluorescence parameters were determined after 7-week growth, aimed to approach the salt tolerance of T. tetragonoides. The suitable salinity for T. tetragonoides growth was 0-400 mol·L^-1, with an upper limit of 600 mol·L^-1, suggesting that T. tetragonoides was a halophyte with higher salt tolerance. The net photosynthetic rate, stomatal conductance, and transpiration rate of T. tetragonoides leaves decreased significantly with increasing salinity, but the stomatal limiting value showed an opposite trend. High salinity could inhibit the leafnet synthetic rate via affecting the closure rate of PSⅡ reaction center, the proportion of the light absorption of photochemical reaction, and the electron transfer rate, and thus, decrease the growth rate of T. tetragonoides. This study showed that T. tetragonoides was a halophyte with high salt tolerance and edible value, and worthy to be popularized in the ecological restoration of coastal wetland.