Abstract: Surface ozone concentration has increased, and more parts of land regions are predicted to become drier under the background of global warming. The stress effects of surface ozone and soil water deficit on the natural plants and crops were briefly presented in this review. Subsequently, the interactive effects of surface ozone and soil water deficit on natural plants and crops were commented intensively, highlighting the response characteristics of stomata conductance and antioxidant system. Two opposite conclusions of injury effects of ozone on the plants under the condition of soil water deficit were raveled out for different species of plants and crops. One opinion deemed that drought promoted the formation of abscisic acid, inducing stomatal closure to reduce the injury effects of ozone. The other opinion argued that ozone accelerated ethylene biosynthesis, and then slowed down the stomatal closure of plants and the stomatal sluggishness occurred, revealing no protection of drought. Meanwhile, the advance of assessment methods for the stress effects of ozone under the condition of soil water deficit was reviewed, and the research ideas of assessment methods for interactive effects of ozone and soil water deficit were further confirmed. Finally, the possible research orientations and approaches of interactive effects between surface ozone and soil water deficit on natural plants and crops were proposed.