关键词: 耐药细菌, 蛋白质分泌, 新抗靶点

Abstract: The gradual depletion of stratospheric ozone layer in atmosphere has led to the increase of solar UV-B radiation that reaches earth surface.The enhanced UV-B radiation would affect plants in various extents through different mechanisms.According to the theories of molecule ecology,the damage of plants by enhanced UV-B radiation is firstly represented as a damage of biomacromolecule,i.e.,photochemical modification.This paper discussed the ways of UV-B radiation affecting environment and plants after the depletion of stratospheric ozone layer,with the focus on the UV-B radiation's effects on the inhibition of protein synthesis and the repair approaches of DNA damage.The prospects on applying the technology of molecule ecology to study the plants' resistant mechanism and DNA damage repair techniques were discussed.

Key words: Drug resistance bacteria, Protein secretion, Target for new antibiotics